Description

Epithalon Biovantage Labs Research Peptide

Epithalon (Ala-Glu-Asp-Gly) is a synthetic tetrapeptide studied for its role in telomerase activation, telomere length maintenance, and neuroendocrine regulatory research models. Biovantage Labs supplies Epithalon in 10mg and 50mg configurations at 99+% purity, verified by batch-specific HPLC and Mass Spectrometry. Domestically fulfilled from Canada. Not for human consumption. Biovantage Labs provides this compound at 99+% purity, confirmed by batch-specific HPLC and Mass Spectrometry analysis, as a lyophilized compound for use in controlled laboratory settings.

Molecular Profile and Chemical Specifications

Specification	Detail
Molecular Formula	C14H22N4O9
Molecular Weight	390.3 Da
Sequence	Ala-Glu-Asp-Gly
Purity	≥99+% (HPLC/MS verified)
Physical Form	Lyophilized white powder
Available Configurations	10mg / 50mg
CAS Number	307297-39-8

 

Selecting the Correct Research Configuration

Configuration	Typical Research Application
10mg	Pilot studies, dose-response investigations, shorter experimental timelines
50mg	Extended longevity protocols, multi-cohort studies, higher-throughput laboratory settings

 

Primary Research Mechanisms

Epithalon and Pinealon are both synthetic peptides originating from pineal gland research and are frequently referenced together in longevity and neuroendocrine ageing literature. Epithalon examined for telomerase activation and melatonin pathway support, Pinealon for pinealocyte biology and blood-brain barrier penetrating neuroprotective properties.

Telomerase Activation and Telomere Length Research

Epithalon is studied for its capacity to activate telomerase reverse transcriptase (TERT) in somatic cell models. Research examines whether Epithalon-induced telomerase expression results in measurable changes to telomere length in cells that do not constitutively express telomerase.

Pineal Gland and Melatonin Regulation

Derived conceptually from pineal peptide research, Epithalon is studied for its influence on pineal gland secretory activity and melatonin biosynthesis. Research in this area examines neuroendocrine consequences of Epithalon administration in aged animal models where pineal function has declined.

Antioxidant Gene Expression and Longevity Models

Epithalon has been examined in longevity research models for its capacity to upregulate antioxidant enzyme expression including superoxide dismutase and catalase, and reduce oxidative damage markers in tissues from aged experimental animals.

Longevity research examining multiple ageing-related pathways simultaneously may include MOTS-c alongside Epithalon. MOTS-c studied for its age-associated decline in circulating levels and its mitochondrial stress response properties, representing a complementary mitochondrial dimension to Epithalon’s telomere-focused research characterisation.

Reconstitution Protocol

• Reconstitute using sterile bacteriostatic water or 0.9% sodium chloride solution
• Introduce diluent slowly along the interior vial wall do not inject directly onto the lyophilized cake
• Swirl gently until fully dissolved do not shake or vortex
• Allow the vial to equilibrate to room temperature before opening to prevent condensation

Storage and Stability

Storage Condition	State	Estimated Stability
-20°C to -80°C	Lyophilized	24+ months
2°C to 8°C	Lyophilized	12 months
Room temperature (20°C)	Lyophilized	3 months
2°C to 8°C	Reconstituted	7 to 14 days

 

Store in a desiccated environment away from UV exposure. Avoid repeated freeze-thaw cycles, which degrade peptide chain integrity over time.

Epithalon Research FAQ

Q: What is the research basis for Epithalon’s telomerase association?

A: Research by Vladimir Khavinson and colleagues at the Saint Petersburg Institute of Bioregulation demonstrated Epithalon-associated upregulation of TERT expression in somatic cell cultures and extended lifespan parameters in rodent models. These findings form the primary research foundation for Epithalon’s telomerase research characterisation, though the precise molecular mechanism of TERT activation remains under investigation.

Q: Is Epithalon for human use?

A: No. Epithalon supplied by Biovantage Labs is strictly for laboratory research purposes. It is not approved for human consumption, veterinary use, or clinical application.

Q: What purity standard does Biovantage Labs apply?

A: Every batch is verified at 99+% purity using HPLC to confirm compound concentration and Mass Spectrometry to confirm molecular identity. Batch-specific COA documentation is available upon request.

Q: Where does Biovantage Labs ship from?

A: All Biovantage Labs products are fulfilled domestically from within Canada, eliminating customs clearance risk and reducing transit time compared to international suppliers.