Description

KPV Biovantage Labs Research Peptide

KPV (Lys-Pro-Val) is a C-terminal tripeptide fragment of alpha-MSH (alpha-Melanocyte-Stimulating Hormone), studied for its anti-inflammatory, antimicrobial, and wound healing properties in preclinical research models. Biovantage Labs supplies KPV at 99+% purity, verified by batch-specific HPLC and Mass Spectrometry. Domestically fulfilled from Canada. Not for human consumption. Biovantage Labs provides this compound at 99+% purity, confirmed by batch-specific HPLC and Mass Spectrometry analysis, as a lyophilized compound for use in controlled laboratory settings.

Molecular Profile and Chemical Specifications

Specification	Detail
Molecular Formula	C16H31N5O4
Molecular Weight	357.45 Da
Sequence	Lys-Pro-Val
Purity	≥99+% (HPLC/MS verified)
Physical Form	Lyophilized white powder
CAS Number	69558-55-0

 

Primary Research Mechanisms

NF-kB Pathway Inhibition and Cytokine Modulation

KPV has been studied in mucosal and systemic inflammation models for its inhibitory effects on NF-kB activation, a master transcriptional regulator of pro-inflammatory cytokine production, including TNF-alpha and IL-6.

Research examining mucosal healing and tissue repair signalling alongside inflammatory resolution may reference BPC-157 as a complementary compound studied in gastrointestinal and wound repair models through distinct FAK-paxillin pathway mechanisms.

Gut Epithelial Research Applications

In intestinal epithelial models, KPV has demonstrated capacity to reduce inflammatory marker expression and promote epithelial barrier integrity. This line of research is distinct from its systemic anti-inflammatory properties.

Antimicrobial Activity

KPV has been investigated in microbiology research for activity against gram-positive and gram-negative bacterial strains, representing a research application beyond its primary anti-inflammatory characterization.

For antimicrobial and innate immune research applications, LL-37, the only known human cathelicidin, represents a related but mechanistically distinct research tool, studied for direct membrane disruption and TLR signalling modulation alongside wound healing applications.

Reconstitution Protocol

• Reconstitute using sterile bacteriostatic water or 0.9% sodium chloride solution
• Introduce diluent slowly along the interior vial wall. Do not inject directly onto the lyophilized cake
• Swirl gently until fully dissolved. Do not shake or vortex
• Allow the vial to equilibrate to room temperature before opening to prevent condensation

Storage and Stability

Storage Condition	State	Estimated Stability
-20°C to -80°C	Lyophilized	24+ months
2°C to 8°C	Lyophilized	12 months
Room temperature (20°C)	Lyophilized	3 months
2°C to 8°C	Reconstituted	7 to 14 days

 

Store in a desiccated environment away from UV exposure. Avoid repeated freeze-thaw cycles, which degrade peptide chain integrity over time.

KPV Research FAQ

Q: Is KPV related to alpha-MSH structurally?

A: Yes. KPV represents the C-terminal tripeptide (positions 11-13) of alpha-MSH. Research has demonstrated that this three-amino acid fragment retains significant anti-inflammatory activity associated with the parent peptide while presenting a simpler molecular structure.

Q: Is KPV for human use?

A: No. KPV supplied by Biovantage Labs is strictly for laboratory research purposes. It is not approved for human consumption, veterinary use, or clinical application.

Q: What purity standard does Biovantage Labs apply?

A: Every batch is verified at 99+% purity using HPLC to confirm compound concentration and Mass Spectrometry to confirm molecular identity. Batch-specific COA documentation is available upon request.

Q: Where does Biovantage Labs ship from?

A: All Biovantage Labs products are fulfilled domestically from within Canada, eliminating customs clearance risk and reducing transit time compared to international suppliers.