Description

HCG Biovantage Labs Research Peptide

HCG (Human Chorionic Gonadotropin) is a glycoprotein hormone studied for its role in LH receptor activation, steroidogenesis signalling, and gonadal axis research models. Biovantage Labs supplies HCG at 99+% purity, verified by batch-specific HPLC and Mass Spectrometry, for controlled laboratory use. Domestically fulfilled from Canada. Not for human consumption. Biovantage Labs provides this compound at 99+% purity, confirmed by batch-specific HPLC and Mass Spectrometry analysis, as a lyophilized compound for use in controlled laboratory settings.

Molecular Profile and Chemical Specifications

Specification	Detail
Classification	Glycoprotein gonadotropin, LH receptor agonist
Subunits	Alpha subunit (92 AA) + Beta subunit (145 AA)
Purity	≥99+% (HPLC/MS verified)
Physical Form	Lyophilized white powder

 

Primary Research Mechanisms

LH Receptor Activation and Leydig Cell Steroidogenesis

HCG binds the luteinising hormone receptor (LHR) with high affinity due to structural homology with LH. In Leydig cell research models, this interaction activates adenylyl cyclase via Gs-coupled signalling, stimulating cAMP production and downstream testosterone biosynthesis.

HPG axis research protocols often examine HCG alongside HGH (Human Growth Hormone) as part of broader endocrine axis characterisation, particularly in models investigating the relationship between gonadal steroidogenesis and growth hormone signalling in reproductive and metabolic research contexts.

Corpus Luteum Support Research

HCG is studied in reproductive biology models for its role in supporting corpus luteum progesterone production following ovulation, a function central to implantation and early gestational research.

HPG Axis Research Applications

HCG serves as a research tool for studying the hypothalamic-pituitary-gonadal (HPG) axis, particularly in models examining the downstream consequences of LH receptor stimulation on steroidogenic enzyme expression and gonadal function.

For reproductive biology research examining the FSH regulatory axis, Follistatin-344, which modulates FSH secretion through activin antagonism, represents a complementary research tool to HCG’s LH receptor-mediated gonadal stimulation within the same hypothalamic-pituitary-gonadal framework.

Reconstitution Protocol

• Reconstitute using sterile bacteriostatic water or 0.9% sodium chloride solution
• Introduce diluent slowly along the interior vial wall do not inject directly onto the lyophilized cake
• Swirl gently until fully dissolved do not shake or vortex
• Allow the vial to equilibrate to room temperature before opening to prevent condensation

Storage and Stability

Storage Condition	State	Estimated Stability
-20°C to -80°C	Lyophilized	24+ months
2°C to 8°C	Lyophilized	12 months
Room temperature (20°C)	Lyophilized	3 months
2°C to 8°C	Reconstituted	7 to 14 days

 

Store in a desiccated environment away from UV exposure. Avoid repeated freeze-thaw cycles, which degrade peptide chain integrity over time.

HCG Research FAQ

Q: Why does HCG bind the LH receptor despite being a distinct hormone?

A: HCG and LH share an identical alpha subunit. Their beta subunits are highly homologous (approximately 80% amino acid identity), and both engage the same LHR binding domain. This structural overlap allows HCG to serve as a functional LH receptor agonist in research models examining LH-mediated signalling.

Q: Is HCG for human use?

A: No. HCG supplied by Biovantage Labs is strictly for laboratory research purposes. It is not approved for human consumption, veterinary use, or clinical application.

Q: What purity standard does Biovantage Labs apply?

A: Every batch is verified at 99+% purity using HPLC to confirm compound concentration and Mass Spectrometry to confirm molecular identity. Batch-specific COA documentation is available upon request.

Q: Where does Biovantage Labs ship from?

A: All Biovantage Labs products are fulfilled domestically from within Canada, eliminating customs clearance risk and reducing transit time compared to international suppliers.