Description

Glutathione Biovantage Labs Research Peptide

Glutathione (GSH) is the primary intracellular antioxidant tripeptide (Glu-Cys-Gly), studied for its role in oxidative stress regulation, xenobiotic detoxification, immune function, and cellular redox homeostasis research models. Biovantage Labs supplies Glutathione at 99+% purity, HPLC/MS verified. Domestically fulfilled from Canada. Not for human consumption. Biovantage Labs provides this compound at 99+% purity, confirmed by batch-specific HPLC and Mass Spectrometry analysis, as a lyophilized compound for use in controlled laboratory settings.

Molecular Profile and Chemical Specifications

Specification	Detail
Molecular Formula	C10H17N3O6S
Molecular Weight	307.3 Da
Sequence	Glu-Cys-Gly (gamma-glutamylcysteinylglycine)
Purity	≥99+% (HPLC/MS verified)
Physical Form	Lyophilized white powder
CAS Number	70-18-8

 

Primary Research Mechanisms

Reactive Oxygen Species Scavenging and Redox Balance

Glutathione is the primary non-enzymatic antioxidant in mammalian cells, reducing hydrogen peroxide and lipid peroxides via glutathione peroxidase. Research examines cellular GSH/GSSG ratios as markers of redox status and oxidative stress burden in experimental models.

Cellular redox research examining glutathione alongside NAD+ allows investigation of the relationship between two distinct but interconnected antioxidant systems. GSH-dependent peroxide reduction and NAD+-dependent sirtuin-mediated stress response, within the same experimental framework.

Phase II Detoxification and Glutathione S-Transferase Research

Glutathione serves as the substrate for glutathione S-transferases, conjugating electrophilic xenobiotics and metabolic byproducts to facilitate their elimination. This phase II detoxification function is studied in hepatocyte research models examining metabolic clearance pathways.

T-Cell Proliferation and Immune Function Research

Intracellular GSH levels influence T-lymphocyte proliferation and cytokine production in immune cell research models. Studies have examined the relationship between cellular redox state, glutathione availability, and immune cell activation thresholds.

For mitochondria-focused oxidative stress research, SS-31 (Elamipretide) is studied in the same experimental context, targeting cardiolipin peroxidation prevention at the inner mitochondrial membrane as a complementary but upstream mechanism to cytosolic glutathione-mediated ROS scavenging.

Reconstitution Protocol

• Reconstitute using sterile bacteriostatic water or 0.9% sodium chloride solution
• Introduce diluent slowly along the interior vial wall do not inject directly onto the lyophilized cake
• Swirl gently until fully dissolved do not shake or vortex
• Allow the vial to equilibrate to room temperature before opening to prevent condensation

Storage and Stability

Storage Condition	State	Estimated Stability
-20°C to -80°C	Lyophilized	24+ months
2°C to 8°C	Lyophilized	12 months
Room temperature (20°C)	Lyophilized	3 months
2°C to 8°C	Reconstituted	7 to 14 days

 

Store in a desiccated environment away from UV exposure. Avoid repeated freeze-thaw cycles, which degrade peptide chain integrity over time.

Glutathione Research FAQ

Q: Why is glutathione studied as a research compound rather than just supplemented directly?

A: Direct cellular uptake of exogenous glutathione is limited by membrane transport mechanisms and rapid extracellular degradation. Research using exogenous GSH examines these transport and stability dynamics, complementing precursor-based approaches (N-acetylcysteine, glycine supplementation) by allowing direct investigation of GSH biology.

Q: Is Glutathione for human use?

A: No. Glutathione supplied by Biovantage Labs is strictly for laboratory research purposes. It is not approved for human consumption, veterinary use, or clinical application.

Q: What purity standard does Biovantage Labs apply?

A: Every batch is verified at 99+% purity using HPLC to confirm compound concentration and Mass Spectrometry to confirm molecular identity. Batch-specific COA documentation is available upon request.

Q: Where does Biovantage Labs ship from?

A: All Biovantage Labs products are fulfilled domestically from within Canada, eliminating customs clearance risk and reducing transit time compared to international suppliers.