Description

AHK-Cu Biovantage Labs Research Peptide

AHK-Cu (Alanine-Histidine-Lysine Copper Complex) is a copper-binding tripeptide studied for its role in hair follicle biology, follicular stem cell activation, and dermal papilla cell research models. Biovantage Labs supplies AHK-Cu at 99+% purity, verified by batch-specific HPLC and Mass Spectrometry. Domestically fulfilled from Canada. Not for human consumption. Biovantage Labs provides this compound at 99+% purity, confirmed by batch-specific HPLC and Mass Spectrometry analysis, as a lyophilized compound for use in controlled laboratory settings.

Molecular Profile and Chemical Specifications

Specification	Detail
Molecular Formula	C15H25CuN6O4 (copper complex)
Molecular Weight	417.9 Da
Sequence	Ala-His-Lys (copper chelate)
Purity	≥99+% (HPLC/MS verified)
Physical Form	Lyophilized powder

 

Primary Research Mechanisms

AHK-Cu research is most meaningfully contextualised alongside GHK-Cu, the structural parent compound that differs only at the N-terminal position. Comparative research between the two copper tripeptides examines whether the Gly-to-Ala substitution produces differences in dermal papilla cell activity, follicular stem cell signalling, or tissue distribution relevant to hair follicle biology.

Dermal Papilla Cell Activation and Hair Follicle Research

AHK-Cu is studied in hair follicle biology research for its capacity to stimulate dermal papilla cell proliferation and upregulate markers of follicular activity. Research examines its effects on follicular stem cell niche signalling in scalp tissue models.

Wnt/beta-Catenin Pathway Modulation

Hair follicle cycling is regulated in part by Wnt/beta-catenin signalling. AHK-Cu research has examined its influence on this pathway in dermal papilla cultures, investigating whether copper tripeptide administration modifies follicular phase transitions in experimental models.

Comparison with GHK-Cu in Hair Research Models

AHK-Cu and GHK-Cu are structurally related copper tripeptides with overlapping but distinct research profiles. While GHK-Cu is primarily characterised in wound healing and collagen synthesis research, AHK-Cu is specifically examined in hair follicle biology, representing a differentiated research application within the copper tripeptide class.

Hair follicle biology research examining growth factor signalling pathways may also reference Follistatin-344 in the context of activin and BMP pathway modulation, signalling axes studied for their roles in follicular cycling and stem cell niche regulation, alongside the copper tripeptide mechanisms examined in AHK-Cu research.

Reconstitution Protocol

• Reconstitute using sterile bacteriostatic water or 0.9% sodium chloride solution
• Introduce diluent slowly along the interior vial wall do not inject directly onto the lyophilized cake
• Swirl gently until fully dissolved do not shake or vortex
• Allow the vial to equilibrate to room temperature before opening to prevent condensation

Storage and Stability

Storage Condition	State	Estimated Stability
-20°C to -80°C	Lyophilized	24+ months
2°C to 8°C	Lyophilized	12 months
Room temperature (20°C)	Lyophilized	3 months
2°C to 8°C	Reconstituted	7 to 14 days

 

Store in a desiccated environment away from UV exposure. Avoid repeated freeze-thaw cycles, which degrade peptide chain integrity over time.

AHK-Cu Research FAQ

Q: How does AHK-Cu differ from GHK-Cu structurally?

A: AHK-Cu (Ala-His-Lys) differs from GHK-Cu (Gly-His-Lys) by a single amino acid substitution, alanine replaces glycine at position 1. This substitution modestly increases molecular weight and alters the peptide’s solubility and tissue distribution profile, properties that are examined in comparative research between the two copper tripeptides.

Q: Is AHK-Cu for human use?

A: No. AHK-Cu supplied by Biovantage Labs is strictly for laboratory research purposes. It is not approved for human consumption, veterinary use, or clinical application.

Q: What purity standard does Biovantage Labs apply?

A: Every batch is verified at 99+% purity using HPLC to confirm compound concentration and Mass Spectrometry to confirm molecular identity. Batch-specific COA documentation is available upon request.

Q: Where does Biovantage Labs ship from?

A: All Biovantage Labs products are fulfilled domestically from within Canada, eliminating customs clearance risk and reducing transit time compared to international suppliers.