Description

SLU-PP-332 – Biovantage Labs Research Peptide

SLU-PP-332 is a synthetic ERR (Estrogen Related Receptor) pan-agonist studied for its effects on mitochondrial biogenesis, oxidative metabolism, and exercise-mimetic signalling in skeletal muscle and cardiac research models. Biovantage Labs supplies SLU-PP-332 at 99+% purity, HPLC/MS verified. Domestically fulfilled from Canada. Not for human consumption. Biovantage Labs provides this compound at 99+% purity, confirmed by batch-specific HPLC and Mass Spectrometry analysis, as a lyophilized compound for use in controlled laboratory settings.

Molecular Profile and Chemical Specifications

Specification	Detail
Classification	ERRα/β/γ pan-agonist
Purity	≥99+% (HPLC/MS verified)
Physical Form	Lyophilized white powder
CAS Number	2140260-82-6

 

Primary Research Mechanisms

ERR Pan-Agonism and Mitochondrial Biogenesis

SLU-PP-332 activates all three estrogen-related receptor subtypes (ERRα, ERRβ, ERRγ), nuclear receptors that regulate the transcription of genes involved in mitochondrial biogenesis, oxidative phosphorylation, and fatty acid beta-oxidation.

Research examining ERR-mediated mitochondrial biogenesis via SLU-PP-332 is often contextualized alongside MOTS-c research. MOTS-c is a mitochondria-derived peptide studied for AMPK pathway activation and mitochondrial stress response signalling, representing a complementary approach to mitochondrial function research through a distinct upstream mechanism.

PGC-1alpha Co-Activation and Metabolic Gene Expression

ERR activation by SLU-PP-332 is studied in the context of PGC-1alpha co-activation, a master regulator of mitochondrial metabolism. Research examines whether SLU-PP-332 reproduces aspects of the transcriptional programme activated by endurance exercise in skeletal muscle models.

Cardiac and Skeletal Muscle Metabolism Research

SLU-PP-332 has been examined in cardiac hypertrophy and heart failure research models as a tool for investigating the role of ERR-regulated mitochondrial function in cardiomyocyte metabolism and energy substrate utilization.

The mitochondrial biogenesis and oxidative phosphorylation research context for SLU-PP-332 overlaps with NAD+ research. NAD+ is required for sirtuin activation and PARP-dependent processes that are themselves regulated downstream of the PGC-1alpha/ERR transcriptional axis SLU-PP-332 engages.

Reconstitution Protocol

• Reconstitute using sterile bacteriostatic water or 0.9% sodium chloride solution
• Introduce diluent slowly along the interior vial wall do not inject directly onto the lyophilized cake
• Swirl gently until fully dissolved do not shake or vortex
• Allow the vial to equilibrate to room temperature before opening to prevent condensation

Storage and Stability

Storage Condition	State	Estimated Stability
-20°C to -80°C	Lyophilized	24+ months
2°C to 8°C	Lyophilized	12 months
Room temperature (20°C)	Lyophilized	3 months
2°C to 8°C	Reconstituted	7 to 14 days

 

Store in a desiccated environment away from UV exposure. Avoid repeated freeze-thaw cycles, which degrade peptide chain integrity over time.

SLU-PP-332 Research FAQ

Q: Why is SLU-PP-332 described as an exercise-mimetic in research contexts?

A: Exercise activates PGC-1alpha and ERR signalling cascades that upregulate mitochondrial density and oxidative capacity in skeletal muscle. SLU-PP-332 pharmacologically activates the same ERR-mediated transcriptional programme, making it a research tool for studying these pathways without the confounding variables of physical exercise protocols.

Q: Is SLU-PP-332 for human use?

A: No. SLU-PP-332 supplied by Biovantage Labs is strictly for laboratory research purposes. It is not approved for human consumption, veterinary use, or clinical application.

Q: What purity standard does Biovantage Labs apply?

A: Every batch is verified at 99+% purity using HPLC to confirm compound concentration and Mass Spectrometry to confirm molecular identity. Batch-specific COA documentation is available upon request.

Q: Where does Biovantage Labs ship from?

A: All Biovantage Labs products are fulfilled domestically from within Canada, eliminating customs clearance risk and reducing transit time compared to international suppliers.